John's best friend and coworker, Eddie (Vince Vaughn), turns down a bounty of $400,000 for each Smith (since he won't get out of bed for anything less than $500,000), but John and Jane find themselves under fire from an army of assassins.
Fending off an attack which blows up their pockmarked house, the Smiths steal their neighbor's minivan and successfully destroy their attackers' three pursuing armored sedans, all while bickering over their fighting styles and newly discovered personal secrets.