Lopez vs Lopez was an American sitcom created by George Lopez, Mayan Lopez and Debby Wolfe that premiered on NBC on November 4, 2022. Wolfe also serves as showrunner and is executive producer. It stars Lopez and his daughter Mayan as fictionalized versions of themselves along with Matt Shively, Brice Gonzalez, Al Madrigal, and Selenis Leyva in supporting roles. In May 2023, the series was renewed for a second season which premiered on April 2, 2024. In May 2024, the series was renewed for a third season which premiered on October 18, 2024. In May 2025, the series was canceled after three seasons.